The combined teams of Akita University, Gunma University and Kobe University found out that the specified enzyme within a cell has the mechanism, which inhibits the effects of the toxicity of glutamic acid to wipe out brain cell. The team put up the result on line Nature dated May 12th, 2010. According to medical professionals, it leads to apply to the treatment of nerve disease, i.e. apoplexia cerebrin, Parkinson’s disease and so on. This enzyme is “INPP4″ in human brain cell. Indeed the glutamic acid has a role, which is required for normal function of human brain, but kills human brain cell.

By the experiment by using the mouse without “INPP4″, the team confirmed that the mouse’s brain cell became extinct and then its muscle contracted bitterly. And also the team confirmed that the death of its brain cell was getting worse by their adding of low-concentrated glutamic acid to its brain cell without “INPP4″.

According to the Professor Takehiko Sadaki, the team leader, they could find one end of the mechanism, which guards the brain cell from attacking of glutamic acid. And also it leads to inhabit the death of cell, the progression of disease and so on if they can enlarge the function of “INPP4″.